Oura Ring Gen 4 sensor data — not clinical measurementsN=1 case study — not validated for clinical decisionsHEV diagnosed Mar 18; interpret findings cautiously in this Day 20 post-ruxolitinib window

Autonomic Recovery Trajectories

Module 1: Comparative Autonomic Analysis
Generated 2026-04-05 19:38 · Henrik (post-HSCT) vs Mitchell (post-Stroke)
HENRIK MEAN HRV
Severe
9.4ms
Below ESC threshold (15ms)
MITCHELL MEAN HRV
Info
50.9ms
Pop. percentile: 72%
HENRIK SLEEP HR
Abnormal
84.3bpm
Elevated
MITCHELL SLEEP HR
Normal
62.1bpm
Normal range
HRV GAP RATIO
Info
5.4x
Mitchell/Henrik (42ms gap)
TRAJECTORY
Stable
Stable
Henrik's 30-day HRV trend

Autonomic Recovery Trajectories

Heart Rate Comparison

Relative Recovery (% of Baseline)

HRV Distribution Comparison

Long-Term Context

Autonomic Coupling (HR vs HRV)

Clinical Context

This report compares two fundamentally different clinical trajectories. Henrik is 2+ years post-allogeneic HSCT with chronic GVHD and severe autonomic dysfunction (HRV consistently below the ESC 15ms threshold). Mitchell is ~15 months post-stroke (bilateral carotid/vertebral artery dissection) with mildly impaired but recovering autonomic function. Direct HRV magnitude comparison is less meaningful than trajectory shape and relative changes within each patient's own range.

Normalization approaches (z-score, percent-of-baseline) allow meaningful cross-patient comparison despite the 5x difference in absolute HRV values. All heart rate values are derived from sleep periods (not readiness scores). Oura readiness 'resting_heart_rate' is a 0-100 score and is never used as bpm.